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Skyscape - USMLE® Question of the Week

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A 28-year-old man comes to the physician for evaluation of infertility. He is healthy and has no other complaints. He eats a high-protein diet and exercises daily in order to be muscular. He weighs 85 kg (187 lb) and is 175 cm (5'8") tall. His temperature is 37.2°C (98.9°F) and blood pressure is 130/82 mm Hg. Physical examination shows small testes. The remainder of the examination shows no abnormalities. Initial laboratory studies show:

Hemoglobin 16 g/dL
Platelet count      200,000/mm3
Leukocyte count       4500/mm3
Serum creatinine     1.4 mg/dL
Serum LH    low
Serum testosterone    normal

 

Which of the following is the most likely cause of his infertility?

A Kinefelter syndrome
B Mumps orchitis
C Exogenous steroid use
D Myotonic dystrophy
E Varicocele
F Cryptorchidism
G Testicular torsion
H Chronic medical illness


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